The Effect of Taeksa-tang for Dyslipidemia: A Systematic Review and Meta-Analysis
نویسندگان
چکیده
Objective: The purpose of this study is to assess the effectiveness and safety using <i>Taeksa-tang</i> for dyslipidemia through a systematic review meta-analysis randomized controlled trials (RCTs).Methods: search was conducted keywords such as “dyslipidemia”, “hyperlipidemia”, “taeksa tang”, “zexie “takusha to” in 12 databases (Pubmed, Cochrane, Embase, ScienceDirect, CNKI, Wanfang, CiNii, RISS, KISS, ScienceON, OASIS, DBpia) on April 13, 2023. There were no limits publication period language. Cochrane’s risk bias (RoB) used evaluate quality studies. A according outcome measurements total effective rate (TER), cholesterol (TC), triglyceride (TG), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), adverse effects, Review Manager web.Results: 9 RCTs selected. In evaluating RoB, 2 studies mentioning random sequence generation, 1 conducting double blindness, 8 without missing values evaluated low risk, while generation high risk. All other parts unclear treatment group (<i>Taeksa-tang</i> or <i>Taeksa-tang-gagam</i>) showed more statistically significant effects compared control (Western medicine Chinese patent medicine) TER (RR : 1.24, 95% CI 1.15 1.34, P<0.00001), TC (MD -1.12, -1.68 -0.56, P<0.0001), TG -1.08, -1.65 -0.51, P=0.0002), HDL-C 0.63, 0.34 0.93, LDL-C -0.81, -1.10 -0.53, P<0.00001). addition, lower 0.30, 0.12 0.74, P=0.008).Conclusion: This suggests that safe use treating dyslipidemia. However, due included studies, clinical need be future increase possibility use.
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ژورنال
عنوان ژورنال: The Journal of Internal Korean Medicine
سال: 2023
ISSN: ['1226-9174']
DOI: https://doi.org/10.22246/jikm.2023.44.3.485